The most common cause for peripheral neuropathy is diabetes. When diabetes is present and not controlled, many patients develop peripheral neuropathy. It is known as diabetic neuropathy However, other issues can result in this condition, such as trauma to the nerves. This can be due to several small injuries or one large traumatic event. Infections within the body, toxic exposures, and metabolic problems can also cause the condition to occur. The lower limbs have to be strong to do what is expected of them. They cushion the impact of daily exercise such as walking running and jogging but that does not mean they cannot weaken through disease.